One of the most infamous incidents of the pre-Civil War antebellum period was the removal of the Cherokees and other southeastern tribes to 'Indian Country' in present day Oklahoma. President Andrew Jackson wanted to free the trans-Mississippi west for the United States. Pandering to the southern states as well as exercising his executive authority, he was able to secure legislation that enabled the removal of the Cherokees from their homeland. While Jackson was stymied by the Seminoles in Florida, he largely got his way, creating a precedent that would continue until the end of the century. Please take a listen!
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